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  • 08월 28일 16시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

Discovery Strategy and Early Development of SKL11197 for Novel Neuropathic Pain Drug

등록일
2008년 8월 18일 16시 42분 52초
접수번호
1556
발표코드
금19G3심 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
금 11시 : 00분
발표형식
심포지엄
발표분야
의약화학 - Recent Drug Development of Chronic Pain and Neuropathic Pain
저자 및
공동저자
문홍식
SK(주) R&D Park, 의약평가 Lab, Korea
Neuropathic pain can be defined as pain caused by lesion or specific disease of the somatosensory change in the peripheral or central nervous system. Until recently, little was known about the mechanisms underlying the neuropathic pain disorders, making the directed development of novel therapies almost impossible. However, the scientific understanding of cellular and molecular basis of neuropathic pain has resulted in the development of an array of animal models to evaluate the potential of new chemical entities in this therapeutic area. Recently, we have discovered SKL11197 that is a novel non-opioid analgesic compound, currently in clinical development for the treatment of neuropathic pain. This presentation provides a progress report of SKL11197, and summaries the obstacles that have hindered the development of physiology-based approaches as the most promising current strategies.

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