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Synthesis and Characterization of Biotin-functionalized Silicon Nanoparticles and Their Application as a Biosensor

등록일
2009년 8월 14일 14시 34분 48초
접수번호
1065
발표코드
33P6포 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
목 <발표Ⅰ>
발표형식
포스터
발표분야
무기화학
저자 및
공동저자
장승현, 최태은, 조보민, 손홍래
조선대학교 화학과, Korea

A new convenient and easy method for a simple room temperature synthesis of Biotin-functionalized Silicon Nanoparticles (BFSi-NPs) with strong blue photoluminescence (PL) for the detection of avidin and streptavidin has been developed. Hydrogen-terminated Si-NPs were synthesized from the reaction of Zintl salt (Mg2Si) with ammonium chloride (NH4Cl).Hydride-covered Si-NPs can be functionalized further by hydrosilylation process with allylamine to terminate amine groups for reaction to biotin group. Prepared BFSi-NPs were characterized by TEM, FT-IR, UV-vis absorption and PL spectrum. The sizes of BFSi-NPs ranged from 4 to 6 nm in diameter.The maximum intensity of emission spectrum was centered at 445 nm with an exitation of 360 nm. Further details will be presented. -This research was financially supported by the Ministry of Coomerce, Industry and Energy (MOCIE) and Korea Industrial Technology Foundation(KOTEF) through the Human Resource Training Project for Regional Innovation-


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