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초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

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  • 09월 04일 13시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

Gradient Surfaces for the Index of Cellular Adhesion Properties

등록일
2009년 8월 21일 15시 16분 36초
접수번호
1522
발표코드
금24I2구 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
금 17시 : 30분
발표형식
구두발표
발표분야
고분자화학 - General Topics on Polymer Science I (대학원생 발표)
저자 및
공동저자
김현정, KHATUA DIBYENDU, 신관우1
서강대학교 화학과, Korea
1서강대학교 화학과 및 바이오융합과정, Korea
The interaction between cells and a solid substrate are very important in tissue engineering and biomedical applications. Many surface properties such as charge, wettability, chemical structure, roughness, and rigidity influence adhesion of cells. To evaluate a favorable cellular response in a specific application, testing of all combinations of various screening factors are a highly time-consuming process. Furthermore the using different substrates at different conditions may complicate the conditions for cell-to-cell comparision. The problem can be minimized by using gradient surfaces, wherein two or more properties vary independently across the specimen. The use of gradients allows cell behavior to be directly compared over a range of different surface properties on a single sample and under identical conditions. In this talk, I would like to present our recent research for preparing charge density/ wettability orthogonal gradient surface and the cell adhesion properties of different types of cells on the surface. Then, we will introduce a simple indexing method to evaluate the cellular adhesion properties to each cells quantitatively, which will be benefit to sort them out depending on their adhesion properties.

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