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학술발표회초록보기

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  • 09월 12일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제110회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Inhibitory Effect of Active Compounds Isolated from Impatiens balsamina(Garden Balsam) for Melanogenesis

등록일
2012년 8월 30일 16시 19분 18초
접수번호
1457
발표코드
BIO.P-761 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
10월 17일 (수요일) 16:00~19:00
발표형식
포스터
발표분야
생명화학
저자 및
공동저자
최병욱, 이봉호1, 임진아2, 이혜숙2
한밭대학교 화학생명공학과, Korea
1한밭대학교 응용화학생명공학부, Korea
2한밭대학교 생명공학과, Korea
The ambient levels of harmful ultraviolet (UV) radiation emitted by the sun are increasing due to destruction of the ozone layer. Therefore, our skin is exposed to more UV radiation and often suffers from various harmful effects of UV. Melaninpigmentation in human skin is a major defense mechanism against UV light of the sun, but abnormal hyperpigmentation such as freckles, chloasma, lentigines and other forms of melanin hyperpigmentation could be serious aesthetic problems. Therefore, potent active agents for the improvement of hyperpigmentation are sought for their cosmetic use. Many chemicals such as hydroquinone, arbutin, kojic acid, and ascorbic acid are well known for their melanogenic inhibitory functions. In this paper, the efficacy of whitening was tstudied with a purifed naphthaquinone from Impatiens balsamina Linne, classified into Balsaminaceae. Methoxynaphtoquinone isolated from Garden Balsam as the active naphthaquinone. For the efficacy of whitening studies, melanin content assay, measurement of cell proliferation, radiometric tyrosinase assay, RNA preparation and reverse transcription-polymerase chain reaction (RT-PCR), western blotting experiments were carried out.

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