KCS

Immunological techniques, and in particular, immunoassay, have proved to be one of the most important tool, which can be applied to investigate the disease biomarkers and pathogenic biological agents which often present at low levels in clinical samples. In order to improve the sensitivity and multiplex detection, a wide variety of assay designs and formats have been developed over the years. In this study, we described the DNA-coated, nano-sized micelles in which the DNA strands play a role as signal generators in an immunoassay. This micelle-based immunoassay was evaluated for quantification of a liver cancer biomarker and the sensitivity of the method was compared with those of the conventional methods.