Asymmetric enamine and iminium catalysis have been provided a wide range of enantiomerically enriched organic compounds which are the key structure for pharmaceuticals and natural product synthesis. In the context of expanding the scope of enamine and iminium organocatalysis, various transition metal complexes have been introduced to asymmetric organocatalytic reactions, rendering unexpected bond formations with high levels of stereoselectivity. In this presentation, our recent accomplishments regarding asymmetric organophotocatalytic reactions using TiO2 and N719/TiO2 photocatalysts, and multistep organocatalytic reactions involving copper complexes will be presented.
1) H.-S. Yoon, X.-H. Ho, J. Jang, H.-J. Lee, S.-J. Kim, H.-Y. Jang, Org. Lett. 2012, 14, 3272.
2) X.-H. Ho, H.-J. Oh, H.-Y. Jang, Eur. J. Org. Chem. 2012, ASAP.
3) X.-H. Ho, M.-J. Kang, H.-Y. Jang, Catal. Sci. & Technol. 2011, 1, 923.