KCS

Recently importance of nonenzymatic glucose detection applying nano-structured material increases to supplement drawbacks of enzymatic sensor, e.g., complexity of device and instability with change of pH and temperature. To match this goal, in present study, hollow gold nanoparticles (hAuNPs) were synthesized in aqueous system containing Co and Au precursor and applied to electrochemical glucose detection. The morphology of hAuNPs was characterized by field emission scanning electron microscope (FE-SEM) and high-resolution transmission electron microscope (HR-TEM). Cyclic voltammetrys (CVs) in acidic condition show that real surface area (RSA) of hAuNPs was enlarged by 40 times at least compared with that of bulk Au electrode. Rotating disk electrode (RDE) voltammetry was performed to find the appropriate potential for glucose oxidation. In amperometric i-t curves at Eapp (applied potential) of -0.1 V, the sensitivity of glucose was 3.86 ?A mM-1 which is much higher than interferent signals such as ascorbic acid (AA), acetamidophenol (AP) and dopamine (DA).