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  • 09월 06일 15시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제112회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Synthesis of Camptothecin-Capped Silicon Quantum Dots for drug Delivery Application

등록일
2013년 9월 5일 14시 48분 50초
접수번호
1381
발표코드
INOR.P-238 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
10월 16일 (수요일) 16:00~19:00
발표형식
포스터
발표분야
무기화학
저자 및
공동저자
백상수, 김성룡, 정성은, 김강빈, 손홍래*
조선대학교 화학과, Korea
Camptothecin(CPT)-capped silicon quantum dots (Si QDs) were successfully synthesized. Optical characterizations of Si QDs were achieved by using ultraviolet-visible (UV-Vis) and photoluminescence (PL) spectroscopy. The morphologies of Si QDs were characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), nuclear magnetic resonance (NMR) and infra-red (IR) spectroscopy. Bare Si QDs and CPT emitted the light at 450 and 425 nm with an excitation wavelength of 400 and 370 nm, respectively. However, CPT-capped Si QDs emitted the light at 570 nm with an excitation wavelength of 480 nm, which shifted to the longer wavelength. Optical characteristic of drug-capped Si QDs were investigated in PSB buffer solution. The release of CPT was investigated by the measurement of fluorescence intensity of Si QDs using UV-vis spectrometer to obtain a release profile. Quantum yields for Si QDs, CPT, and CPT-capped Si QDs were measured. This research was financially supported by the Ministry of Education (MOE) and National Research Foundation of Korea(NRF) through the Human Resource Training Project for Regional Innovation. (2012H1B8A2026282).

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