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학술발표회초록보기

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  • 02월 20일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제113회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Graphene Oxide Embedded Thin Sol-Gel Film for Small Molecule Analysis by Laser Desorption/Ionization Mass Spectrometry

등록일
2014년 2월 17일 12시 58분 16초
접수번호
1243
발표코드
ANAL.P-522 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
4월 16일 (수요일) 16:00~19:00
발표형식
포스터
발표분야
분석화학
저자 및
공동저자
이광빈, 배상은, 허성, 차상원*
한국외국어대학교 화학과, Korea
Graphene oxide (GO) has been widely used for a matrix of laser desorption/ionization (LDI) mass spectrometry(MS) of small molecules because GO has relatively lower matrix noise than conventional MALDI matrixes such as 2,5-dihydroxybenzoic acid and also because GO effectively ionizes some neutral molecules such as oligosaccharides which are often hard to be ionized by conventional MALDI matrixes. However, use of carbon-based materials is not desirable for time-of-flight (TOF) mass spectrometers since carbon nanomaterials stick to TOF electronics and therefore cause the instability of the MS operation. In order to overcome this issue, we developed GO embedded sol-gel film substrates for LDI MS of small molecules. Our results showed that the GO sol-gel film matrix substrate produced a much lower background noise than the aqueous GO particle matrix. This suggests that ablated carbon materials were significantly reduced when using the sol-gel film substrates. In addition, GO-embedded sol-gel film produced very clear and intense profiles of small metabolites in the region of m/z 100 - 300. Various examples of small molecule analysis with the GO film will be demonstrated in this presentation.

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