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  • 02월 20일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제113회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Development of New Two-photon Absorbing Materials and Fluorescent Probes: Linear and Bent Type Pi-Extended Coumarin Derivatives

2014년 2월 17일 15시 07분 01초
ORGN.O-2 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
금 10시 : 15분
유기화학 - Oral Presentation for Young Organic Chemists
저자 및
김도경, 안교한*
포항공과대학교 화학과, Korea

Two-photon (excitation) microscopy (TPM) combined with the laser excitation technology has arrested recent attention in the bioimaging area because it shows several advantageous features over one-photon excitation microscopy (OPM). TPM is most often emphasized to be “less photo-toxic, less photo-bleaching and less photo-damaging”. In addition, TPM enables deeper tissue (700-1100 nm) imaging with high spatio-temporal resolution, and thus is particularly useful for tissue imaging where auto-fluorescence becomes serious in the case of OPM. The primary aim of this research is to develop new two-photon materials which show desirable photo-physical properties for bioimaging, overcoming some drawbacks of known dyes such as acedan and coumarin derivatives. This research is also focused on the studies of new platforms for the development of two-photon fluorescent probes for biologically important analytes, based on the reaction-based sensing approach. As a results, we have developed novel π-extended coumarin dyes, which show very promising properties as two-photon excitable dyes and also molecular shape-dependent luminescent behaviours. #Ref: (a) Kim, Kim, D.; Sambasivan. S.; Nam. H.; Kim. K. H.; Kim. J. Y.; Joo. T.; Lee. K.; Kim. K.; Ahn. K. H. Chem. Commun. 2012, 48, 6833. (b) Kim, I,; Kim, D.; Ahn. K. H. Asian J. Org. Chem. 2012, 1, 60.