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학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

현재 가능한 작업은 아래와 같습니다.
  • 02월 20일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제113회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Robust biosensors based on graphene oxide: towards practical implementation in biomedicine

등록일
2014년 2월 18일 15시 34분 10초
접수번호
1262
발표코드
KCS3-3 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
금 11시 : 40분
발표형식
심포지엄
발표분야
KCS Tutorial on Friday : Principle and Application of Graphene
저자 및
공동저자
민달희
서울대학교 화학과, Korea
To design practically useful biosensors based on new nanomaterials, one should understand and fully utilize chemical/physical properties to detect molecular changes during certain biochemical transformations in a biological system. Moreover, the new system should overcome limitations of conventional assay methods?detection limits, cost issues, labors, efficiencies, quantitativeness, reproducibility, etc. In this talk, I will introduce recent studies which harness graphene derivatives for developing bioanalytical platforms to quantitatively analyze various enzyme activities and biomarkers including helicase and microRNA. The systems rely on attractive interaction between graphene oxide and nucleic acids and fluorescence quenching by graphene oxide. Recently, we employed one of the graphene-based bioassay systems to anti-viral drug screening and identified potent hit compounds to treat hepatitis C. This study clearly shows that a new nanobio-technology can be routinely implemented in drug discovery, providing many advantages over conventional methods.

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