Among nerve agents, Tabun (GA) is very unique since it includes a P-CN bond whereas others include a P-F bond. The use of fluorescent molecules in sensing agents specifically is an ongoing aim.1-3 The selective detection of Tabun is very important. In this study, a salicylaldehyde oxime based on a BODIPY system was introduced and developed for the detection of nerve agent-related molecules. The fluorescence intensity of the B-SAL-OXIME species increases in the presence of DECP, whereas it decreases in the presence of DCP and DEMP (limit of detection = 997 nM). Benzonitrile formation in the novel fluorescent B-SAL-OXIME system was elucidated using model substrates.
Key words: Nerve agent, Tabun, BODIPY, Salicylaldehyde oxime
1. Y. J. Jang, O. G. Tsay, D. P. Murale, J. A. Jeong, A. Segev and D. G. Churchill Chem. Commun., 2014, 50, 7531-7534
2. K. Kim, O. G. Tsay, D. A. Atwood and D. G. Churchill, Chem. Rev., 2011, 111, 5345-5403.
3. Y. J. Jang, D. P. Murale and D. G. Churchill Analyst, 2014, 139, 1614-1617