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학술발표회초록보기

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  • 02월 26일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제115회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Au nanoparticle decorated Graphene sheet for plasmon-enhanced photoluminescence immunoassay platform

등록일
2015년 2월 26일 14시 04분 09초
접수번호
1434
발표코드
ANAL.P-585 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
4월 15일 (수요일) 16:00~19:00
발표형식
포스터
발표분야
분석화학
저자 및
공동저자
김정효, 오상진1, 이재범2,*
부산대학교 인지메카트로닉스 공학과, Korea
1부산대학교 인지메카트로닉스공학과, Korea
2부산대학교 나노메디컬공학과, Korea

Metal-nanoparticle?functionalized graphene, in particular, graphene sheets containing Au nanoparticles (Au NPs), have generated considerable interest due to their unique optical and electrical characteristics. In this study, we successfully produced graphene sheets decorated with Au NPs (AuGrp) using phytochemicals as reducing agents. During this reaction, Au ions intercalated into the layered graphene flakes and were then reduced into NPs, exfoliating the graphene sheets. The physicochemical properties of the AuGrp nanocomposites were characterized, and the exfoliation process was investigated using a molecular dynamics simulation of Au NPs between graphene sheets. Using antibody (Ab) modified AuGrp sheets and quantum dots, a plasmonic-enhanced photoluminescence immunoassay of tuberculosis (TB) antigen (aG) CFP-10 was demonstrated for a potential application of these materials. The enhancement of photoluminescence (PL) response was monitored depending on the various TB aG concentrations from 5.1 pg/mL to 51 μg/mL, and the detection limit for CFP-10 was 4.5 pg/mL. Furthermore, the selectivity was demonstrated with Ag85 as the other TB aG, and PL enhancement was not observed in this case. Therefore, AuGrp based immunoassay showed the potential for biosensor application.


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