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학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

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  • 09월 08일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제116회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Regio- and Stereospecific Copper-Catalyzed Allylic Substitution with Readily Accessible 1,1-Alkyldiboronates [우수포스터상]

등록일
2015년 8월 27일 16시 56분 23초
접수번호
1070
발표코드
ORGN.P-397 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
10월 15일 (목요일) 11:00~12:30
발표형식
포스터
발표분야
유기화학
저자 및
공동저자
김정훈, 박진영, 조승환*
포항공과대학교(POSTECH) 화학과, Korea
Transition metal-catalyzed allylic alkylation represents one of the most powerful tools to form carbon-carbon bonds in organic syn-thesis. Among these reactions, the copper-catalyzed allylic alkyl-ation has become an efficient strategy to provide branched alkyl compounds. While considerable progress has been made in the copper-catalyzed allylic alkylations between allylic electrophiles and organometallics reagents such as dialkylzinc, Grignard, alkyllithium and alkylaluminium, limited functional group compatibility, and air or moisture sensitivity of organometallic reagents often limit their synthetic applications. Moreover, these reactions typically requires cryogenic reaction temperature to achieve a high level of selectivity. In this poster, we will present a copper(NHC)-catalyzed (NHC = N-hetrocyclic carbene) γ-selective allylic alkylation reaction of al-lylic chlorides with 1,1-alkyldiboronates. This methodology represents a rare example of a highly γ-selective allylic alkylation employing readily accessible 1,1-alkyldiboronates and the reaction opens the door for the future development of enantio and diastereoselective variants.

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