초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

현재 가능한 작업은 아래와 같습니다.
  • 09월 08일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제116회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Yttrium(III) incorporated layered double hydroxide for bio-application

2015년 9월 3일 16시 33분 21초
MAT.P-478 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
10월 16일 (금요일) 13:00~14:30
저자 및
엄새란, 양재훈, 최진호*
이화여자대학교 화학.나노과학과, Korea
Yttrium-90 (90Y) is one of the popular candidates as the radiotherapeutic species. A pure β-emitter 90Y has fewer environmental radiation restrictions, and it has a suitable for the irradiation of larger tumors because of its long residence time property. In the case of 90Y microspheres as radiotherapy agents, they are injected into an organ diseased with cancer. When they are trapped in a small blood vessel linked the cancer, they kill the cancer cells due to emit highly β-rays of 90Y and are remained inside a human body. Therefore it is necessary to develop the novel radiotherapeutic materials, which should be eliminated from body after radioactive of 90Y for a cancer treatment. Layered double hydroxide (LDH) incorporating Y is a good candiate material due to the bio-compatiblity, that is, LDH is non-toxic material and slowly dissolved in the body fluid condition. In the present study, the LDHs of Mg2Al1-xYx?(CO3)?nH2O (x = 0 ? 1) were successfully synthesized via coprecipitation and hydrothermal treatment. With increasing the Y3+ content, the particle size of prepared LDHs decreased and the hexagonal morphology was changed to thin round plate-like one. According to X-ray diffraction analysis, with increasing Y3+ content (x) from 0 to 0.4, a and c lattice parameters of MgAlY-LDHs were changed from 3.04 to 3.07 ? and from 22.7 to 24.0 ?, respectively, indicating that the increase of yttrium contents led to the expansion between the hydroxide layers. According to FT-IR analysis, a peak at 1357 cm-1 corresponding to the O-C-O symmetric vibration band of CO32- with D3h symmetry was observed for x =0. However, in case of Y3+ incorporated LDHs (x = 0.1 ? 0.4), peaks at 1510 cm-1 and 1385 cm-1 corresponding to asymmetric and symmetric vibration bands were observed. These differences are attributed to the lattice distortion by incorporating larger yttrium ions than Mg2+ and Al3+ into the LDH lattice.