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Thin Membrane Transducers for Bio/Chemical Sensing

Submission Date :
2 / 28 / 2006 , 10 : 50 : 47
Abstract Number :
97022812456
Presenting Type:
Symposium
Presenting Area :
물리화학 - 물리3. Fundamental and Practical Aspects of Nanochemistry
Authors :
이정훈, 차미선, 김일책, 최준보
서울대학교 기계항공공학부,
Assigned Code :
금12I3심 Assigend Code Guideline
Presenting Time :
금 14시 : 30분
This talk introduces a thin polymer membrane as a mechanical sensing element that offers a device structure that can measure molecular interaction forces. A thin membrane transducer is designed and fabricated for monitoring bio/chemical reactions through chemo-mechanical transduction with high sensitivity. A specific molecular binding event on the surface of the membrane causes the deflection due to a surface force. The deflection can be detected by the capacitance change across a gap between the membrane and a substrate. The device structure offers an inherently robust configuration in a liquid with selective sensitivity to the surface reaction. A capacitive detection enables compact devices in a microarray format. This work demonstrates the detection of various bio/chemical reactions: the formation of a self-assembled monolayer (SAM), liquid spreading, a protein interaction, and a DNA hybridization.