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학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

현재 가능한 작업은 아래와 같습니다.
  • 01월 01일 09시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

Searching for Functional Molecules based on Molecular Recognition

등록일
2006년 3월 20일 09시 38분 02초
접수번호
1253
발표코드
금19G1분념 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
금 09시 : 30분
발표형식
분과기념
발표분야
유기화학 - 유기2. Today and Tomorrow in Organic Chemistry - 2. Current Trends in Organic Reactions
저자 및
공동저자
홍종인
서울대 화학과,
A major focus of our research is on the development of selective synthetic receptors and sensors for biorelevant target molecules such as ions, peptides, carbohydrates and proteins. In particular, we present several fluorescent and chromogenic PPi sensors, which show high sensitivity and selectivity for PPi ions compared to other anions including ATP and ADP. This system can be applied for biochemical and analytical enzyme assays involving NTP and PPi. We present a new approach to sensing structurally similar carbohydrates in which arrays of synthetic differential MIP receptors along with pattern recognition can simultaneously identify multiple analytes. We are also investigating a new method for the construction of fluorescent probes that are useful for detecting a specific protein in homogeneous solution. We introduced a new approach to biotin-streptavidin assays based on a molecular tripod which consists of biotin, a fluorescent donor and acceptor. The emission intensity of the molecular tripods plus streptavidin increases compared to that of molecular tripods in the absence of streptavidin. We have been also involved in the development of self-assembled superstructures based on metal-ligand and hydrogen bonding interactions. Examples of the unidirectional helical structures will be presented.

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