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학술발표회초록보기

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  • 02월 19일 23시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제119회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Silicon Nanoparticle based Magnetic Resonance Imaging Probe for Early-Stage Cancer Diagnosis

등록일
2017년 2월 16일 17시 08분 21초
접수번호
5145
발표코드
ANAL2.O-47 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
금 10시 : 40분
발표형식
구두발표
발표분야
분석화학 - Oral Presentation of Young Analytical Chemists Ⅱ
저자 및
공동저자
최익장, 김도경, 이영복*
한양대학교 바이오나노공학과, 응용화학과, Korea
Silicon-based nanoparticle has been attracting lots of interest in the field of magnetic resonance (MR) applications because of its specific features of biocompatibility and flexible surface chemistry. Since a core region of the crystalline Si NPs is mostly protected from paramagnetic centers on its surface defect sites, the Si NPs conventionally represent extremely long depolarization times, resulting in high MR signal-to-noise ratio with minimum background signals. In order to synthesize size-controlled Si NPs, we utilized magnesiothermic reduction of silica nanoparticles at various reduction temperature and time. In addition to the traditional synthetic approach, we produce 29-silicon enriched NPs with synthesized 29Si-TEOS for the purpose of additional signal enhancements. The enriched Si NPs in combination with hyperpolarization technique provide sufficient MR signals for in vitro and in vivo MR applications.

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