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학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

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  • 09월 05일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제120회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Overview of single-genome sequencing technologies for lineage tracing of somatic cells

등록일
2017년 8월 31일 15시 44분 47초
접수번호
2410
발표코드
ACBI-2 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
목 09시 : 25분
발표형식
심포지엄
발표분야
Analytical Chemistry-Life Chemistry - [Analytical Chemistry Division - JASIS (Japan) - Life Chemistry Division Joint Symposium] Super-Resolution Optical Microscopy and Single-Cell Analysis
저자 및
공동저자
Young Seok Ju
Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Korea
All cells that constitute the human body are direct descendants, through a lineage of mitotic cell divisions, of the fertilized egg. During normal mitotic cell division, the genome is replicated with very high, but not absolute, precision, which leads to the incorporation of somatic mutations throughout the course of an individual's life. The somatic mutations then will be inherited to all direct descendants of the specific cell. Therefore, these post-zygotic somatic can be used in lineage tracing as markers if the sequencing accuracy is sufficiently high. In my talk, I would like to overview the acquisition of somatic mutations in human cells, pros and cons of many different single-genome technologies and to discuss genome sequencing strategies in my laboratory which may enable the lineage trancing of many adult human cells.

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