abs

학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

현재 가능한 작업은 아래와 같습니다.
  • 09월 05일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제120회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Assessment of Phototoxicity Inhibition of Flavone-based Materials

등록일
2017년 7월 30일 15시 55분 15초
접수번호
3003
발표코드
ANAL1.O-5 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
목 09시 : 24분
발표형식
구두발표
발표분야
Analytical Chemistry - Oral Presentation of Young Analytical Chemists I
저자 및
공동저자
Sung Eun Lee, Tian Tian, Seog Woo Rhee*
Department of Chemistry, Kongju National University, Korea
In this work, we investigated the phototoxicity inhibition process of flavone-based materials using the 3T3 NRU assay, an in vivo acute phototoxicity evaluation method. Amiodarone HCl and chlorpromazine HCl were used as phototoxic materials, and chrysin and apigenin were used as photoinhibition inhibitors. The phototoxicity index, PIF value and MPE value, were calculated based on the cell viability measured as a function of concentration. When cells were treated with solutions containing both chlorpromazine and flavone-based materials, both chrysin and apigenin reduced the phototoxicity of chlorpromazine by UVA. In addition, we will discuss the cytotoxic and phototoxic mechanisms of each material and the phototoxicity inhibition process of flavone-based materials.

상단으로