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  • 09월 05일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제120회 대한화학회 학술발표회, 총회 및 기기전시회 Application of gradient generating microdroplet-based chips for rapid and sensitive bioanalysis

2017년 8월 31일 09시 58분 31초
ANAL2.O-34 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
금 10시 : 27분
Analytical Chemistry - Oral Presentation of Young Analytical Chemists II
저자 및
Jinhyeok Jeon, JAEBUM CHOO*
Department of Bionano Technology, Hanyang University, Korea
Microfluidic technology have recently emerged as an efficient tool for the study of various chemical or biological reactions. Recently, we reported that high-throughput chemical or biological reactions could be performed in a continuous flow microfluidic channel with an automatic manner. However, there is a “memory effect” problem in the continuous flow system. Samples in the continuous stream could be stacked in the wall of a microfluidic channel, and they may occur unwanted flow hindrance. To resolve this problem, we recently developed a novel gradient microdroplet system. In this system, the sample stacking problem can be solved since two-phase liquid/liquid segmented flow reduces the memory effect. A serial dilution of reagent can be achieved in a stepwise manner using microfluidic concentration gradient generators. Then, desired concentrations of a reagent were sequentially trapped by a small volume of droplets to prevent the sample stacking. We believe that this microdroplet system will be of significant utility in monitoring chemical and biological effects for various concentrations of a reagent.