abs

학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

현재 가능한 작업은 아래와 같습니다.
  • 02월 19일 10시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제121회 대한화학회 학술발표회, 총회 및 기기전시회 안내 The nanoparticles embedded bioorthogonal catalysts for the intracellular imaging

등록일
2018년 2월 1일 18시 33분 12초
접수번호
3508
발표코드
ANAL1-4 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
목 16시 : 40분
발표형식
심포지엄
발표분야
Analytical Chemistry - Recent Advances in Analytical Chemistry I: Optical Sensor Platform Based Nanobio Materials
저자 및
공동저자
Youngdo Jeong
Biomedical Research Institute, Korea Institute of Science and Technology, Korea

Chemical/biological information from intracellular imaging has accelerated the improvement of medical science and industry. The intracellular imaging through the direct delivery of organic dyes are challenging due to their photo-bleaching issue, short life-time, weak signaling. We have fabricated the biorthogonal catalytic system that can be generating the fluorescence dye intracellularly. This system is based on the water-soluble nanoparticles embedded the hydrophobic transition metal catalysts in their ligand shell. Also, the catalytic activity of the system can be regulated by controlling the binding between the nanoparticle and host molecules. The intracellular catalytic systems were used for imaging triggered cleavage of allylcarbamates for pro-fluorophore activation. The universal usage of this system will be applied not only intracellular imaging, but also diagnostics and therapeutics.


상단으로