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  • 02월 19일 10시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제121회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Synthesis and Biological Evaluation of Ergostenol and Its Glycosides

등록일
2018년 2월 13일 11시 04분 11초
접수번호
5947
발표코드
ORGN.P-547 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
4월 19일 (목요일) 11:00~12:30
발표형식
포스터
발표분야
Organic Chemistry
저자 및
공동저자
Dowon Yoon, YOUNGKYOUNG CHO1, TAEHOON LEE2, Hakwon Kim2,*
Applied Chemistry, Kyung Hee University, Korea
1Department of Chemisty, Kyung Hee University, Korea
2Department of Applied Chemistry, Kyung Hee University, Korea

Natural spinasterol-glucose (3-O-β-D-glucopyanosylspinasterol), isolated from Stewartia koreana leaves, has been identified as a compound to exhibit a potent anti-inflammatory activity. Further biological investigations for spinasterol glycosides were needed, but due to the difficulty and inefficiency of isolation and synthesis of natural spinasterol and spinasterol glucose it has not been done. Therefore, we have designed and synthesized a new sterol, such as ergostenol((3β, 5α)-ergost-8(14)-en-3-ol), as the substitute for spinasterol. In present study, we will describe the synthesis and biological activities of ergostenol and its glycosides.


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