abs

학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

현재 가능한 작업은 아래와 같습니다.
  • 02월 19일 10시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제121회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Design and synthesis of TPH1 inhibitors for the obesity

등록일
2018년 2월 13일 12시 02분 18초
접수번호
5984
발표코드
MEDI.P-655 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
4월 19일 (목요일) 11:00~12:30
발표형식
포스터
발표분야
Medicinal Chemistry
저자 및
공동저자
Eunjung Bae, HAUSHABHAU PAGIRE1, SUVARNA HAUSHABHAU PAGIRE1, JIN HEE AHN*
Department of Chemistry, Gwangju Institute of Science and Technology, Korea
1Department of Chemistry, Gwangju Institute of Science and Technology, India
Obesity is a global public health problem. The obesity epidemic has been growing in developed nations, including the United States, for decades. Moreover, this epidemic has spread to developing nations. The negative consequences of obesity have been quantified as exceeding those of either alcohol abuse or smoking. Serotonin (5-hydroxytryptophan) is a hormone that regulates emotions in the central system. In the peripheral system, it is a hormone related to induction of obesity. TPH1 (tryptophan hydroxylase 1) is a protein that synthesizes serotonin, thus TPH1 inhibitor could be a promising target for the treatment of obesity. In this meeting, discovery of TPH1 inhibitors will be presented.

상단으로