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  • 02월 19일 10시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제121회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Water-soluble Quantum Dot Nanoprobes using multidentate ligangds for Point-of-Care Lateral Flow Assay

등록일
2018년 2월 13일 16시 20분 08초
접수번호
6126
발표코드
MAT.P-558 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
4월 20일 (금요일) 11:00~12:30
발표형식
포스터
발표분야
Material Chemistry
저자 및
공동저자
Jinyeong Kim, oh seok kwon1,*
BNT research center, Korea Research Institute of Bioscience & Biotechnology, Korea
1BNT research center, KRIBB, Korea
Lateral flow assays (LFA) are simple devices intended to detect the presence (or absence) of a target analyte in sample (matrix) without the need for specialized and costly equipment. Although, this diagnostic tools have provided attractive advantages, the limitations such as low sensitivity and storage remains as challenges. In this research, we provided quantum dots (QDs) based LFA with high sensitivity and long-term stability. Especially, QDs were synthesized under liquid state, so they have high stability and quantum yield. Moreover, the surface of the QDs was modified with multidentate ligands, such as carboxylic terminal groups and the HRP2 antibody were easily conjugated by EDC-NHS coupling reaction. The HRP2 antibody-conjugated QDs were used for LFA application and they showed higher detection level comparing to the conventional Au nanoparticle-based LFA kits.

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