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  • 02월 19일 10시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제121회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Fabrication of Anisotropic Plasmonic Au@Si Core-Shell Nanoparticles for Bioanalytical Dual Imaging

2018년 2월 7일 15시 01분 24초
ANAL2.O-10 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
금 09시 : 47분
Analytical Chemistry - Oral Presentation of Young Analytical Chemists II
저자 및
nara lee, Seunghyun Lee1,*
nanochemical, Gachon University Global Campus, Korea
1Department of Nanochemistry, Gachon University, Korea
One of the emerging research area in nanomedicine is development of non-invasive techniques for the bioimaging, diagnosis and therapy of disease. Advancement of platform technologies for a wide range of potential applications is significant because of the complexity of the living organism and cytotoxicity of employed materials. Especially, plasmonic gold nanoparticles have attracted a great deal of recent interest due to their unique optical properties such as strong electromagnetic field enhancement and strong light absorption. Silicon and its oxide derivatives have become a material of significant interest recently for imaging and drug delivery due to their chemical stability and optoelectronic properties. Anisotropic plasmonic gold nanoparticle are very useful for surface enhanced Raman scattering (SERS) which has been widely applied for chemical analysis or molecular detection. Biocompatibility and nanoporous structure of the silicon nanoparticle can be applied to magnetic imaging based on dynamic nuclear polarization (DNP) and drug delivery for theragnostics. Here, we have fabricated Si-Au core/shell nanoparticles using Au NRs and Au BPs. First, Au NRs and Au BPs were synthesized by a seed-mediated method and silica is subsequently overcoated by a stöber method. The overcoating onto surface on gold nanoparticles with cetyltrimethylammonium bromide has been completed using syringe pump. The overcoating reaction gives shells as thin as around 25 nm thickness. Next, the silica layer is replaced to silicon by reduction using magnesium powder. We analyzed the core-shell nanoparticle using scanning electron microscopy(SEM), transmission electron microscopy(TEM), UV-Visible spectroscopy, X-ray diffraction(XRD) and Raman spectroscopy.