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제122회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Poly(carprolactone-hydroquinone) Oxalate (CQX) as ROS-sensitive degradable polymers

등록일
2018년 8월 13일 19시 08분 29초
접수번호
0187
발표코드
POLY.P-2 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
10월 18일 (목요일) 11:00~12:30
발표형식
포스터
발표분야
Polymer Chemistry
저자 및
공동저자
SeungYi Son, Heeju Kim, Hanbyul Jang, Byeongmoon Jeong*
Department of Chemistry and Nano Science, Ewha Womans University, Korea
PCL-OX (Polycaprolactone Oxalate) was reported as a fast degradable PCL and is a promising biodegradable material that solves the slow degradation problem of PCL over 2-3 years. In particular, degradation of the polymer was accelerated in the presence of hydrogen peroxide or reactive oxygen species (ROS). Therefore it can be used in a variety of biomedical applications where fast biodegradable polymers are needed. In continuation of the research, poly(carprolactone-hydroquinone) Oxalate (CQX) was synthesized by condensation polymerization using PCL diol 530, hydroquinone, and oxalyl chloride. Degradation of CQX was investigated as a function of ROS concentration.

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