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제122회 대한화학회 학술발표회, 총회 및 기기전시회 안내 A Ratiometric pH-Sensor Based on Dye-conjugated Upconversion Nanoparticles

등록일
2018년 8월 30일 11시 38분 52초
접수번호
2021
발표코드
PHYS.P-319 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
10월 19일 (금요일) 11:00~12:30
발표형식
포스터
발표분야
Physical Chemistry
저자 및
공동저자
Manoj Kumar Mahata Male, Kang Taek Lee1,*
Chemistry, Gwangju Institute of Science and Technology, India
1Division of Physical Chemistry Department of Chemi, Gwangju Institute of Science and Technology, Korea
Intra-cellular pH-sensing is of huge importance to understand the cellular activities and detection of diseases in an early stage. Therefore, the optical pH-nanoprobes that can work in biological environment, is an immediate requirement in medical research and diagnostics. In this work, the dye-conjugated upconversion nanoparticles (UCNP) have been prepared as pH-sensing system based on the based on fluorescence resonance energy transfer. We have analysed the variation of luminescence emission in ratiometric manner from the pH-dependent fluorescein dye and pH-insensitive NaYF4: Tm3+/Yb3+ UCNPs to measure the pH of the system. The synthesized upconversion nanoparticles are useful for biological application, due to their low cytotoxicity, high photostability, low photobleaching and lack of autofluorescence in biological materials.

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