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  • 09월 03일 23시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제122회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Synthesis of A2B corroles for the application of photodynamic therapy

등록일
2018년 8월 30일 16시 36분 48초
접수번호
2124
발표코드
MEDI.P-326 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
10월 18일 (목요일) 11:00~12:30
발표형식
포스터
발표분야
Medicinal Chemistry
저자 및
공동저자
Jihyeon Baek, Ung Jeong 1, Yonghwang Ha*
Department of Pharmaceutical Science, Jungwon University, Korea
1Department of pharmaceutical science, Jungwon University, Korea
Many researches are interested in developing tumor-specific destruction method. As an alternative therapeutic skill, photodynamic therapy (PDT) attracts great interests due to its high temporal and spacial selectivity to tumor cells. PDT is based on the photosensitizers which can generate singlet oxygen by energy transfer from triplet excited state sensitizers to molecular oxygen in ground state. Herein, we designed two types of free base A2B corroles and phosphorus corroles as photosensitizers, synthesized, and characterized the photophysical properties via measuring of UV-vis absorbance, and emission spectra, etc. For the next step, we are planning to synthesize various halogenated metallocorroles and investigating phosphorescence properties and application for tumor removal potential in cellular level.

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