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  • 02월 28일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제123회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Poly(acrylic acid-co-maleic acid)-coated Gadolinium Oxides Nanoparticles as T1 MRI contrast agents.

등록일
2019년 2월 1일 13시 46분 26초
접수번호
3040
발표코드
PHYS.P-100 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
4월 19일 (금요일) 11:00~12:30
발표형식
포스터
발표분야
Physical Chemistry
저자 및
공동저자
Yeong Ji Jang, Gang Ho Lee1,*
Kyungpook National University, Korea
1Department of Chemistry, Kyungpook National University, Korea
Paramagnetic Nanoparticles have received great attention in biomedical research because of their physicochemical properties. They have electron spin magnetic moment which improve the quality of magnetic resonance imaging (MRI) preferred technique in diagnosing diseases. Especially, gadolinium oxide (Gd2O3) nanoparticles (Gd(III), s = 7/2) has one of the largest paramagnetism because 4f-unpaired electrons contribute to magnetic moment. So Gd2O3 nanoparticles have been used as promising T1 MRI contrast agents (T1 MRI-CAs). In this research, We synthesized Gd2O3 nanoparticles coated by the ligands named Poly(acrylic acid-co-maleic acid) (Poly(AA-co-MA)). The colloidal suspension showed great ability as a MRI-CA through relaxivity 1 value. Also, Their biocompatibility was proved by measuring in vitro cellular cytotoxicities.

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