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  • 02월 28일 17시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제123회 대한화학회 학술발표회, 총회 및 기기전시회 안내 LDBBA catalyzed hydroboration of unsaturated hydrocarbons and imines with pinacolborane (HBpin)

2019년 2월 14일 15시 05분 15초
ORGN.P-341 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
4월 18일 (목요일) 11:00~12:30
Organic Chemistry
저자 및
Ashok Kumar Jaladi, Duk Keun An*
Department of Chemistry, Kangwon National University, Korea

Hydroboration is an important and fundamental reaction system in organic chemistry. Hydroboration of unsaturated hydrocarbons such alkynes, alkenes is an effective and straight-forward method for the preparation of alkene and alkyl boronates which are versatile building blocks in various chemical transformations and metal mediated cross-coupling reactions.1-2 In recent days much attention is focusing on catalyzed hydroborations, leading to its rapid application starting from transition metals to main group-alkaline earth elements, and lanthanide complexes. In addition, synthesis of secondary amines through C=N bond reduction is a straight forward and often used in organic synthesis. The traditional hydrogenation with transition metals is well examined. Whereas, hydride reduction with LiAlH4 or NaBH4, is unattractive due to their poor yields. Therefore, efficient and sustainable method with lower active reductants are needed. During the course of our search for efficient reductions; we have identified and reported selective hydroboration of aldehydes and ketones with pinacolborane and commercial reagents as catalysts.3-4 In continuation, the present abstract demonstrates that LDBBA catalyzed hydroboration of unsaturated hydrocarbons and imines (Scheme). 1. Chong, C. C.; Kinjo, R. ACS Catal. 2015, 5, 3238− 3259. 2. Obligacion, J. V.; Chirik, P. J. Nat. Rev. Chem. 2018, 2, 15-34. 3. Shin, W. K.; Kim, H.; An, D. K. Tetrahedron. 2018, 74, 6310-6315. 4. Yang, S. J.; Jaladi, A. K.; Kim, K. H.; Gundeti, S.; An, D. K. Bull. Korean Chem. Soc. 2019, 40, 34–38.