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  • 09월 10일 16시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제124회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Size-controlled one-pot polyol synthesis and characterization of D-glucuronic acid-coated ultrasmall BiOI nanoparticles as potential x-ray contrast agent

등록일
2019년 8월 20일 16시 05분 17초
접수번호
0532
발표코드
PHYS.P-150 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
10월 17일 (목요일) 11:00~12:30
발표형식
포스터
발표분야
Physical Chemistry
저자 및
공동저자
Adibehalsadat Ghazanfari, Gang Ho Lee1,*
Department of Chemistry, Kyungpook National University, Iran
1Department of Chemistry, Kyungpook National University, Korea
A polyol method is extremely useful for preparimg metal-containing nanoparticles coated with hydrophilic and biocompatible ligands for biomedical applications. In this study, D-glucuronic acid coated BiOI nanoparticles were prepared in one-pot using this method. The particle diameter was controlled by varying the solvent volume such that the particle diameter decreased with increasing solvent volume: nanoparticles with average diameters of 1.9 (ultrasmall) and 6.1 nm were prepared at two solvent volumes. The x-ray attenuation properties of the ultrasmall nanoparticles were investigated because of their suitability for in vivo biomedical applications. D-glucuronic acid-coated ultrasmall BiOI nanoparticles were superior to the commercial molecular iodine contrast agent Ultravist® in terms of x-ray attenuation, and showed the highest x-ray attenuation efficiency (η) of ∼21 HU/mM [Bi] that has ever been reported thus far, proving their potential as an extremely powerful x-ray contrast agent.

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