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제124회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Quantitative multi-element analysis for assessing environmental exposure during early childhood with deciduous teeth

등록일
2019년 8월 27일 13시 31분 20초
접수번호
1642
발표코드
ANAL.P-151 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
10월 18일 (금요일) 11:00~12:30
발표형식
포스터
발표분야
Analytical Chemistry
저자 및
공동저자
Youngjoo Kal, Sangwon Cha1,*
Hankuk University of Foreign Studies, Korea
1Department of Chemistry, Hankuk University of Foreign Studies, Korea
Recently, deciduous teeth have received a great attention as new biomarkers for evaluating early-life human exposure due to their unique developmental process. Dentine layers of deciduous teeth are formed from the 14th to 19th week of pregnancy, so chemicals exposed during fetal period could be accumulated. In addition, exposure chemicals after birth are separated from prenatal exposure chemicals by a neonatal line which is formed at birth. These features make it possible for deciduous to have much longer tracking period than conventional biomarkers such as mother's blood, urine or placenta, cord blood. Our group has tried to develop a method for quantitatively measuring several elements from a baby tooth matrix. A developed method mainly consisted of a tooth matrix digestion by a microwave-aided acidic digestion and multi-element analysis by inductively coupled plasma dynamic reaction cell mass spectrometry (ICP DRC MS). Since deciduous teeth do not have a reference material, we used an NIST SRM 1486 bone meal, which is known to have the most similar components to those of tooth materials, for optimizing the analytical method. Our results showed that our method could successfully measure contents of over ten elements both from NIST SRM 1486 and from individual deciduous tooth samples.

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