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제124회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Development and validation of a multi-element quantitation method for whole blood samples by ICP DRC MS

2019년 8월 27일 14시 07분 12초
ANAL.P-152 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
10월 18일 (금요일) 11:00~12:30
Analytical Chemistry
저자 및
Jun young Park, Sangwon Cha1,*
Chemistry, Hankuk University of Foreign Studies, Korea
1Department of Chemistry, Hankuk University of Foreign Studies, Korea
In exposomics research that tries to measure all the exposures of an individual and reveal how the measured exposures relate to health, whole blood samples are one of the most widely used biomatrices due to its relatively easy accessibility and procedural simplicity. There have been many studies which tried to quantify elements from whole blood samples. Most of these studies focused on toxic heavy metals. For example, the US CDC laboratory manual published in 2014 described a method for quantitation of five toxic elements –cadmium, lead, manganese, mercury, and selenium- from whole blood samples. In this study, based on the US CDC laboratory manual, we tried to develop a multi-element analysis method with whole blood samples that can cover up to 12 elements including toxic heavy metals. In order to confirm the reliability of our method, we also performed validation of our method which include evaluation of detection limits, selectivity, precision, accuracy, and linearity.