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  • 09월 10일 16시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제124회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Hydrogel Fibers Network for Three-Dimensional Cell Cultures

등록일
2019년 8월 28일 16시 22분 26초
접수번호
1709
발표코드
MEDI.O-4 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
목 09시 : 45분
발표형식
구두발표
발표분야
Medicinal Chemistry - Oral Presentation of Young Discovery Chemists
저자 및
공동저자
Sungrok Wang, Myung-Han Yoon*
School of Materials Science and Engineering, Gwangju Institute of Science and Technology, Korea
In biomedical engineering, electrospun fibers have been extensively used as porous scaffolds for a variety of three-dimensional (3-D) cell cultures however there still are practical issues such as low optical transparency, unfavorable mechanical stiffness, poor dimension controllability, etc. Herein, we fabricated hydrogel fiber suspension with zwitterionic properties by grinding electrospun fibers. The resultant suspension of hydrogel fibers exhibited excellent biodegradability, high optical transparency, controllable mechanical properties, and stable dispersion in water. When the oppositely charged fiber suspensions were mixed together, the hydrogel fibers were entangled forming hydrogel fibers network with microscale porosity. Finally, the entangle fibers can act as 3-D cell culture scaffold and, it was demonstrated that stiffness, overall diameter, and swelling ratio of hydrogel fibers can be easily modulated to optimize for various applications.

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