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  • 09월 10일 16시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제124회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Scalable Synthesis of Superparamagnetic Fe3O4 Nanoclusters for Bioseparation and Bioimaging

2019년 8월 28일 18시 10분 31초
MAT.P-377 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
10월 17일 (목요일) 11:00~12:30
Material Chemistry
저자 및
Jeonghyo Kim, Van Tan Tran1, SangJin Oh, Jaebeom Lee2,*
Research Institute of Materials Chemistry, Chungnam National University, Korea
1Research Institute of Materials Chemistry, Chungnam National University, Vietnam
2Chemistry, Chungnam National University, Korea

Magnetic nanoparticles (MNPs) have had a significant impact on a wide range of advanced applications in the academic and industrial fields. For such applications, the nanoparticles require specific properties, including hydrophilic behavior, uniform and tunable dimensions, and good magnetic properties. However, it remains challenging to achieve a reproducible industrial-scale synthesis of magnetic nanoparticles with such desired properties as precise control of particle growth is difficult. In our current work, we demonstrated a gram-scale synthesis of hydrophilic magnetic nanoclusters based on a one-pot solvothermal system. The synthesized particles have a close-packed superstructure of iron oxide nanocrystals (~13 nm in diameter) that exhibiting hydrophilicity, superparamagnetism, high magnetic responsiveness, and colloidal stability. Additional silica coatings provided further stability and functionality, which was confirmed by in vitro magnetic separation and in vivo fluorescence imaging. These applications verified that the properties of the magnetic nanoclusters fulfilled the various requirements of biological systems. It is expected that this large-scale synthesis of hydrophilic Fe3O4 nanoclusters could be widely used for biomedicine, energy storage, photonics, and catalysis applications, among others.