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학술발표회초록보기

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  • 09월 11일 00시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제124회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Human Cancer Biomarker Discovery with Proteomics

등록일
2019년 8월 29일 16시 59분 56초
접수번호
1903
발표코드
ANAL3-2 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
금 10시 : 20분
발표형식
심포지엄
발표분야
Analytical Chemistry - Recent Trends in Mass Spectrometry
저자 및
공동저자
Wonryeon Cho
Department of Bio-nanochemistry, Wonkwang University, Korea
Targeted proteomics using affinity chromatography (AC) has been used for identifying and quantifying cancer-related proteins through cancer and normal plasma on breast, colon, and lung cancer. Some proteins were found to be potential cancer marker candidates based on their elevation in various cancer patients. Recently, exosomes from lung cancer plasma were used to identify exosomal proteins. Exosomes are cell-derived nanovesicles that are rich source of novel biomarkers in the diagnosis and prognosis of disease. Exosomes were individually extracted from 46 patients plasma of lung cancer through size-exclusion chromatography. Each exosome sample was pooled into three TNM groups. Each group samples were analyzed multiple times on nLC-MS/MS system with various methods for exosomal protein identification from lung cancer plasma.

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