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  • 09월 10일 16시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

제124회 대한화학회 학술발표회, 총회 및 기기전시회 안내 Construction of Thiazole Derivatives using Liquid-Phase Synthesis

등록일
2019년 9월 9일 15시 19분 36초
접수번호
1992
발표코드
MEDI.P-285 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
10월 17일 (목요일) 11:00~12:30
발표형식
포스터
발표분야
Medicinal Chemistry
저자 및
공동저자
SuJeong Kim, Yeeun Noh, Hyeok Jin Lee, Jimin Moon, YoungBeom Kim, Taeho Lee*
Department of Pharmacy, Kyungpook National University, Korea
Liquid-phase organic synthesis has become an important technology for the construction of chemical libraries for several years. The construction of chemical library is necessary to search of drug-like compound and Liquid-phase synthesis can be used usefully. Through this method, we have studied about the construction of heterocyclic compounds because heterocyclic compounds serve as key structural component of bioactive molecules. In this study, we have an interested in heterocyclic compounds containing thiazole moiety. we tried to construct a small molecule library based on thiazole moiety. Thiazole itselfs is not useful, but its derivatives are effective against dyes, sulphas, vitamin B (thiamin), fungicides, blood vessel blockers, analgesics, antiviral hypertension. For decades, humanity has been trying to reduce the side effects of many drugs. Therefore, we have developing a synthetic protocol to efficiently produce thiazole derivatives and generate a thiazole derivative library.

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