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대한화학회 제124회 학술발표회 및 총회 Synthesis and Biodegradation Evaluation of Biodegradable Microcapsules for Medical and Industrial Applications

등록일
2019년 8월 28일 15시 11분 29초
접수번호
3014
발표코드
ANAL1.O-14 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
목 09시 : 39분
발표형식
구두발표
발표분야
Analytical Chemistry - Oral Presentation of Young Analytical Chemists I
저자 및
공동저자
Jiwon Kim, Donghyeok Jo1, Youngbok Lee2,*
Department of Bionano technology, Hanyang University, Korea
1Department of Bio Nano Engineering, Hanyang University, Korea
2Department of Bio-Nano Engineering, Department of, Hanyang University, Korea
Microcapsules are materials used in various fields such as medicine, cosmetics, and fabric softeners, and microcapsules are often synthesized into microplastics in household goods. However, as plastics are the main culprit of ecosystem destruction and environmental pollution, many countries are declaring war on plastics around the world. Therefore, we attempt to synthesize biodegradable microcapsules and check their biodegradation in various ways. We selected biodegradable polymers through theoretical investigations and synthesized cellulose-based microcapsules using biodegradation studies of NMR-based cellulose using enzymes. Synthesis of microcapsules was confirmed by microscopy, IR and NMR, and residual isocyanates that may remain during microcapsule synthesis were analyzed by IR and NMR to check for harmlessness to the human body. To confirm the biodegradability of the synthesized microcapsules, we performed BOD, COD and cellulase-based degradation experiments.The enzymic study was measured by NMR, UV spectrum, and SEM, and the change over time was confirmed. The biodegradation of microcapsules could be predicted through the change of line width, absorbance, and morphology. The biodegradability tendency of the samples shown by each experiment did not deviate significantly from the expectations based on the raw material used for the synthesis. Currently, we are conducting more various control experiments, focusing on experiments to verify whether the changes caused by cellulase are correct, and trying to develop biodegradation confirmation methods applicable to microcapsules that will be useful in medicine and industry.
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