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소개 및 활동/사업
역대 학회상 수상자
대한화학회 창립 75주년
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09월 20일 16시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능
제126회 대한화학회 학술발표회 및 총회
Combined Exposure Assessment of Quaternary Ammonium Compounds (QACs) in Various Consumer Chemical Products (CCPs)
2020년 9월 3일 15시 48분 15초
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화 10시 : 28분
Analytical Chemistry -
Oral Presentation of Young Analytical Chemists II
, Han Bin Oh
Chemistry, Sogang University, Korea
Department of Chemistry, Sogang University, Korea
Various biocidal chemicals included in the consumer chemical products (CCPs) have sacrificed many lives and impacted greatly on human health. To effectively regulate the chemicals in the CCPs, the Ministry of Environment have begun to strengthen the regulations on the usage of biocides in the CCPs. One of the most widely used biocidal chemicals in CCPs are quaternary ammonium compounds (QACs). QACs are a group of chemicals having a structure of NR4+, positively charged nitrogen atom with four alkyl chains (R) covalently connected to it. In this research, an analytical method using liquid chromatography tandem mass spectrometry (LC-MS/MS) were applied to identify and quantify 2 different QACs, benzylalkyldimethylethylammonium chloride (BAC), alkyltrimethylammonium bromide (ATMAB). To carry out the exposure assessment, the guidelines suggested by the US Environmental Protection Agency (US EPA) and Korea Ministry of Environment were followed to specify the exposure routes and scenarios. In this research, two different exposure routes, ingestion and dermal contact, were investigated to estimate how much QACs a person is exposed to while using CCPs. QACs in 4 different CCPs, fabric softener, mouthwash, eyedrop and hand sanitizer, were identified and quantified using LC-MS/MS. Furthermore, exposed amount of QACs through various routes were investigated, so that the overall assessment of body exposure to the QACs in the CCP could be estimated. Acknowledgement This research was supported by a grant (2018002490001) through the Technology Program for Establishing Biocide Safety Management, funded by the Korea Environmental Industry & Technology Institute.
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