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A novel preparative method for radiometal Cu-64 using enrich Ni-64

등록일
2007년 8월 3일 11시 17분 18초
접수번호
0056
발표코드
35P265포 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
목 <발표Ⅱ>
발표형식
포스터
발표분야
의약화학
저자 및
공동저자
김정영, 이교철1, 최재용1, 하현준, 안광일2
한국외국어대학교 화학과,
1한국원자력의학원 방사성의약품개발실,
2한국원자력의학원 방사성의약품 개발실,
Cu-64 study for PET has recently been reported to be particularly effective in tumor diagnosis. This utility of Cu-64 depends on the proper radioactivity of positron emission and stability in water. However, the Cu-64 production has never been studied in Korea. The aim of our study was to widen the use of Cu-64 in molecular imaging based on PET tech. The Cu-64 production used here was prepared according to simple method modified from Welch group in Washington Univ. In particular, we could obtain in about 99% of radiochemical purity through making the equipment for enrich Ni plating and separation. For nuclear reaction, we carried out pn reaction under about 30uA/15MeV at cyclotron. On the other hand, the imaging ability of Cu-64 was determined by microPET. This development of Cu-64 production may be extended to the synthesis of new radiotracer for molecular imaging and tumor therapy.

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