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129th General Meeting of Korean Chemical Society & Exposition A serotonin selective voltammetric sensor comprised of DNA and carbon nanotubes composites

Submission Date :
2 / 25 / 2022 , 20 : 29 : 16
Abstract Number :
129022525718
Presenting Type:
Poster Presentation
Presenting Area :
Electrochemistry
Authors :
Jingjing Li, Hye Jin Lee*
Department of Chemistry, Kyungpook National University, Korea
Assigned Code :
ELEC.P-707 Assigend Code Guideline
Presenting Time :
April 15 (FRI) 11:00~13:00
In this work, a biosensor based on modifying positively charged poly(diallyldimethylammonium)-wrapped oxidized single-walled carbon nanotubes (PDDA-oSWCNTs) layer and negatively charged serotonin (5-HT)-specific aptamer layer onto the gold nanoparticles deposited carbon electrode was fabricated for the selective detection of serotonin. This developed biosensor showed linear detection ranges of 50-500 nM with a limit of detection of 2 nM in buffer solution. The biosensor was also applied to analyze the serotonin concentrations in clinical serum samples.