abs

학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

현재 가능한 작업은 아래와 같습니다.
  • 09월 05일 13시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

Au(I)-Catalyzed 5-and 6-exo-Selective Cyclizations of Acetylenic Silyl Enol Ethers

등록일
2007년 8월 14일 20시 26분 33초
접수번호
0803
발표코드
34P250포 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
금 <발표Ⅲ>
발표형식
포스터
발표분야
유기화학
저자 및
공동저자
최용식, 강동진, 이필호
강원대학교 화학과,
Development of useful methods for annulating a five- and six-membered ring onto alkenes and alkynes continues to be of great importance for the prepartion of cyclic carbon frameworks. The catalysis of organic reaction by gold-catalysts has received in the past only little attention because of the preconceived opinion that gold is expensive and inert. Herein, we try to explain efficient method for ring annulation onto α,β-unsaturated ketone. For example, 1,4-Addition of dimethyl propargyl malonate to α,β-unsaturated ketone in the presence of TBSOTf gave acetylenic silyl enol ether as a precursor (THF, 0 oC, 82 %). Treatment of acetylenic silyl enol ethers with 5 mol % PPh3AuCl / 5 mol% AgOTf (DCE, 0.2 M, 80 oC, 9 h) gave carbocyclic compounds in good yield.

상단으로