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Organoboranes are versatile synthetic intermediates for the preparation of a wide range of organic molecules. We have recently reported an highly efficient protocol for the conjugate addition of Bis(pinacolato)diboron to various α,β-unsaturated carbonyl compounds. We have also developed the first asymmetric β-boration of acyclic α,β-unsaturated carbonyl compounds that provides ready access to funtionalized chiral organoboron compounds under mild reaction conditions. Excellent yields and high enantiomeric excesses were obtained using planar chiral ligands at room temperature.
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KCS