abs

학술발표회초록보기

초록문의 abstract@kcsnet.or.kr

결제문의 member@kcsnet.or.kr

현재 가능한 작업은 아래와 같습니다.
  • 02월 22일 16시 이후 : 초록수정 불가능, 일정확인 및 검색만 가능

Structural Studies of the Stereochemical Cycloadducts of Bicyclolactone via Diels-Alder Reaction

등록일
2008년 2월 13일 21시 18분 12초
접수번호
1197
발표코드
30P231포 이곳을 클릭하시면 발표코드에 대한 설명을 보실 수 있습니다.
발표시간
목 <발표Ⅰ>
발표형식
포스터
발표분야
분석화학
저자 및
공동저자
김진, 조천규1, 원호식
한양대학교 응용화학과,
1한양대학교 화학과,
Bicyclolactones obtained from the Diels-Alder cycloaddition of 3,5-dibromo-2-pyrone can undergo various palladium catalyzed cross coupling reactions to afford aryl bicyclolactones. Bromo-bicyclic diene furnished two different diastereomers endo-form (62%) and exo-form (38%) upon cycloadditions with N-Et maleimide (NEM), and their stereo chemistries were identified with NMR. In this study, The NMR signal assignments of each isomer was completely accomplished with COSY, TOCSY, NOESY and ROESY. Distance of numerous protons were obtained based on the NOE cross peak intensities of NOESY spectrum. On the basis of these distance data, distance geometry(DG) with 2D-NOE backcalculation and molecular dynamic(MD) were carried out to determine the isomer structure of endo-form and exo-form.

상단으로