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| Type |
Poster Presentation |
| Area |
유기화학 |
| Room No. |
포스터발표장 |
| Time |
4월 20일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-199 |
| Subject |
A study on the synthesis of fully conjugated units for carotenoid |
| Authors |
강세인, 구상호1,*
명지대학교 에너지융합공학과, Korea
1명지대학교 화학과, Korea
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| Abstract |
Carotenoids are important natural products Which have medical, biological effect. We studied the synthesis of the natural carotenes using sulfone-mediated coupling reaction, protection of alcohol and double elimination. Recently, lycopene and lycophyll were efficiently produced by using Julia-Kocienski olefination, which can be obtained by the coupling the C10 geranyl benzothiazolyl(BT) sulfone with C20 crocetin dialdehyde.
The Julia-Kocienski olefination in the total synthesis of carotenoid natural products were demonstrated using the C5 BT-sulfone containing an acetal group, which was prepared as a chain-extension unit of Apocarotenoids. The double Julia-Kocienski olefination of the C5 BT-sulfone with C10 2,7-dimethyl-2,4,6-octatrienedial and deprotection of the resulting acetal groups efficiently produced C20 crocetin dialdehyde. Above protocol for apocarotenoid can be used the natural carotenoid and electronic conductivity of carotenoids.
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| E-mail |
sein_style@naver.com |
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119th General Meeting of the KCS