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| Type |
Symposium |
| Area |
Current Trends in Organic Chemistry Ⅱ: Molecular Recognition |
| Room No. |
302호 |
| Time |
FRI 09:00-: |
| Code |
ORGN2-1 |
| Subject |
Stimuli-responsive Synthetic Chloride Trasporters across Lipid Membranes |
| Authors |
정규성
연세대학교 화학과, Korea |
| Abstract |
Ion transport across lipid membranes is a pivotal process in the biological systems. In particular, there have been many different chloride channels that are precisely on and off by biological signals. Dysfunction of these channels causes serious diseases such as cystic fibrosis, Batter’s syndrome, Best disease and Myotonia. With hope of potential future use in the treatment of these channelopathies, a large variety of synthetic molecules that can transport chloride ions across lipid and cellular membranes have been studied for the last two decades. We have been focused on the development of small synthetic molecules featuring the controlled activity of chloride transport according to external stimuli such as light and enzymes, which possibly enables delivering the ions in a spatiotemporal manner. Details will be discussed in the presentation |
| E-mail |
ksjeong@yonsei.ac.kr |
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119th General Meeting of the KCS