The interest in the development of methods for the synthesis of tetracyclic structures in which an isoindole fragment is annulated with quinoline, or benzazepine fragments is due to the wide spectrum of physiological activity and the widespread occurrence of such structures in nature. Among them the structure of isoindolobenzazepine is tetracyclic compounds including both isoindolinone and benzazepine fragments. In this study a new attempt has been designed to form the skeleton by intramolecular Michael addition and Friedel-Craft type reaction