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| Type |
Poster Presentation |
| Area |
유기화학 |
| Room No. |
포스터발표장 |
| Time |
4월 20일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-216 |
| Subject |
Total synthesis of resorcylic lactones: Aternariol using BBr3-promoted
intramolecular cyclization without formation of side products
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| Authors |
권소현, 김태현1,*
인천대학교 화학과, Korea
1인천대학교 자연과학대학 화학과, Korea
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| Abstract |
Alternariol, main metabolite of toxin-producing Alternaria fungi, leads to crop losses by fouling of some fruits such as tomatoes, apples despite of low toxicity as compared with others. Therefore, the isolation of alternariol is an important issue for minimization of crop losses and toxicological residual risks. However, only sub-milligram amounts of the Alternariol can be obtained from infected fruits, so artificial synthesis of Alternariol is necessary. Total synthesis of alternariol is already proposed in other studies, but the final synthesis step gave poor yield, together with the generation of side-products. For this reason, we tried to search new high-yielded procedures and conditions, and the new synthesis of alternariol using BBr3-promoted intramolecular cyclization has been developed. |
| E-mail |
ksh920514@hanmail.net |
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119th General Meeting of the KCS