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|
| Type |
Poster Presentation |
| Area |
유기화학 |
| Room No. |
포스터발표장 |
| Time |
4월 20일 (목요일) 11:00~12:30 |
| Code |
ORGN.P-219 |
| Subject |
Diversification of pyrrolo[2,3-d]pyrimidine by microwave mediated Cu-catalyzed N-arylation coupling reaction |
| Authors |
박승영, 염을균*
충남대학교 화학과, Korea
|
| Abstract |
Arylpyrrolo[2,3-d]pyrimidines have shown wide range of biological activitys, such as anti microbial, inhibition of protein kinases and antagonist effects to receptors, etc. Thermal C-N coupling reaction needs long time and requires harsh conditions to synthesize these derivatives. but microwave reaction has the advantage of reducing time and reducing side effects compared to thermal reaction.
In this study, we will discuss about using the microwave unlike thermal reaction then N-arylated pyrrolo[2,3-d]pyimidine and their derivatives are synthesized within a short reaction time and high yield. |
| E-mail |
musung275@naver.com |
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119th General Meeting of the KCS